Drug Detail


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Drug Name Ublituximab
Trade Name
Synonyms LFB-R603|TG-1101|TG-20|TGTX-1101
Drug Descriptions

Ublituximab (TG-1101) is a monoclonal antibody that targets CD20 that may induce complement-dependent and antibody-dependent cell-mediated cytotoxicity against B-cells expressing CD20, potentially resulting in increased B-cell death (PMID: 23611989, PMID: 32351164).

DrugClasses CD20 Antibody 21
CAS Registry Number 1174014-05-1
NCIT ID C91078


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Ublituximab + Umbralisib Acalabrutinib Ublituximab Umbralisib 0 2
Cyclophosphamide + Doxorubicin + Prednisone + Ublituximab + Umbralisib + Vincristine Sulfate Cyclophosphamide Doxorubicin Prednisone Ublituximab Umbralisib Vincristine Sulfate 0 1
Edralbrutinib + Ublituximab + Umbralisib Edralbrutinib Ublituximab Umbralisib 0 1
Ibrutinib + Ublituximab Ibrutinib Ublituximab 0 1
Ibrutinib + Ublituximab + Umbralisib Ibrutinib Ublituximab Umbralisib 0 1
Lenalidomide + Ublituximab + Umbralisib Lenalidomide Ublituximab Umbralisib 0 1
Pembrolizumab + Ublituximab + Umbralisib Pembrolizumab Ublituximab Umbralisib 0 1
Tazemetostat + Ublituximab + Umbralisib Tazemetostat Ublituximab Umbralisib 0 1
TG-1801 + Ublituximab TG-1801 Ublituximab 0 2
Ublituximab Ublituximab 0 2
Ublituximab + Umbralisib Ublituximab Umbralisib 0 7
Ublituximab + Umbralisib + Venetoclax Ublituximab Umbralisib Venetoclax 0 3

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