Drug Detail


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Drug Name TG-1801
Trade Name
Synonyms NI-1701|TG1801|TG 1801
Drug Descriptions

TG-1801 (NI-1701) is a bispecific antibody that binds to CD47 and CD19 on B cells and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, potentially leading increased antitumor immune response and phagocytosis of tumor cells (PMID: 29743205, PMID: 35538512).

DrugClasses CD19 Antibody 17 CD47 Antibody 27 Immune Checkpoint Inhibitor 155
CAS Registry Number NA
NCIT ID C166137


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Therapy Name Drugs Efficacy Evidence Clinical Trials
TG-1801 TG-1801 0 2
TG-1801 + Ublituximab TG-1801 Ublituximab 0 2

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