Drug Detail


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Drug Name Mivavotinib
Trade Name
Synonyms TAK-659|TAK659
Drug Descriptions

Mivavotinib (TAK-659) is an inhibitor of spleen tyrosine kinase (SYK), which may lead to B-cell inhibition and antitumor activity (PMID: 32327472).

DrugClasses SYK Inhibitor 14
CAS Registry Number 1312691-33-0
NCIT ID C113162


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bendamustine + Mivavotinib Bendamustine Mivavotinib 0 1
Bendamustine + Mivavotinib + Rituximab Bendamustine Mivavotinib Rituximab 0 1
Cyclophosphamide + Doxorubicin + Mivavotinib + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Mivavotinib Prednisone Rituximab Vincristine Sulfate 0 1
Gemcitabine + Mivavotinib Gemcitabine Mivavotinib 0 1
Ibrutinib + Mivavotinib Ibrutinib Mivavotinib 0 1
Ixazomib + Mivavotinib Ixazomib Mivavotinib 0 1
Lenalidomide + Mivavotinib Lenalidomide Mivavotinib 0 1
Mivavotinib Mivavotinib 0 5
Mivavotinib + MLN1117 MLN1117 Mivavotinib 0 0
Mivavotinib + Nivolumab Mivavotinib Nivolumab 0 1
Mivavotinib + NKTR-214 Mivavotinib NKTR-214 0 1
Mivavotinib + Paclitaxel Mivavotinib Paclitaxel 0 1
Mivavotinib + Venetoclax Mivavotinib Venetoclax 0 1

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