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Drug Name Serabelisib
Trade Name
Synonyms INK1117|TAK-117|MLN-1117|MLN1117
Drug Descriptions

Serabelisib (MLN1117) selectively inhibits PI3K alpha kinase, including mutations of PIK3CA, and therefore, targets the PI3K/Akt/mTOR pathway with potentially less toxicity than pan-PI3K inhibitors (PMID: 28490463, PMID: 30168905).

DrugClasses PIK3CA inhibitor 18
CAS Registry Number 1268454-23-4
NCIT ID C98844

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Mivavotinib + Serabelisib Mivavotinib Serabelisib 0 0
Paclitaxel + Sapanisertib + Serabelisib Paclitaxel Sapanisertib Serabelisib 0 1
Sapanisertib + Serabelisib Sapanisertib Serabelisib 0 4
Serabelisib Serabelisib 4 3


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