Drug Detail


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Drug Name 9-ING-41
Trade Name
Synonyms 9 ING 41|Elraglusib
Drug Descriptions

9-ING-41 is an ATP-competitive inhibitor that selectively blocks GSK-3beta, potentially leading to cell cycle arrest and apoptosis, and antitumor effects including inhibition of cell proliferation and tumor growth (PMID: 31894292, PMID: 29846250).

DrugClasses GSK-3beta Inhibitor 4
CAS Registry Number 1034895-42-5
NCIT ID C156792


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Therapy Name Drugs Efficacy Evidence Clinical Trials
9-ING-41 9-ING-41 0 2
9-ING-41 + Carboplatin 9-ING-41 Carboplatin 0 3
9-ING-41 + Carboplatin + Paclitaxel 9-ING-41 Carboplatin Paclitaxel 0 1
9-ING-41 + Docetaxel + Gemcitabine 9-ING-41 Docetaxel Gemcitabine 0 2
9-ING-41 + Doxorubicin 9-ING-41 Doxorubicin 0 1
9-ING-41 + Fluorouracil + Irinotecan + Leucovorin + Losartan + Oxaliplatin 9-ING-41 Fluorouracil Irinotecan Leucovorin Losartan Oxaliplatin 0 1
9-ING-41 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin 9-ING-41 Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
9-ING-41 + Gemcitabine 9-ING-41 Gemcitabine 0 1
9-ING-41 + Gemcitabine + Nab-paclitaxel 9-ING-41 Gemcitabine Nab-paclitaxel 0 1
9-ING-41 + Gemcitabine + Nab-paclitaxel + Retifanlimab 9-ING-41 Gemcitabine Nab-paclitaxel Retifanlimab 0 1
9-ING-41 + Irinotecan 9-ING-41 Irinotecan 0 2
9-ING-41 + Lomustine 9-ING-41 Lomustine 0 1

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