Drug Detail


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Drug Name GSK2830371
Trade Name
Drug Descriptions

GSK2830371 is an allosteric, small molecule inhibitor of PPM1D, which results in increased phosphorylation Ppm1d substrates and may result in tumor growth inhibition (PMID: 24390428).

DrugClasses PPM1D Inhibitor 3


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + GSK2830371 Carboplatin GSK2830371 0 0
Cytarabine + GSK2830371 Cytarabine GSK2830371 0 0
Doxorubicin + GSK2830371 Doxorubicin GSK2830371 0 0
GSK2830371 GSK2830371 0 0
GSK2830371 + Idasanutlin GSK2830371 Idasanutlin 0 0
GSK2830371 + Nutlin-3 GSK2830371 Nutlin-3 0 0

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