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Drug Name L-NMMA
Trade Name
Synonyms NG-Monomethyl-L-arginine acetate|Tilarginine
Drug Descriptions

Tilarginine (L-NMMA) is a pan-nitric oxide synthase inhibitor, which may decrease proliferation and migration of tumor cells (PMID: 25849745).

CAS Registry Number 17035-90-4


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + L-NMMA + Nab-paclitaxel Alpelisib L-NMMA Nab-paclitaxel 0 1
Cyclophosphamide + Docetaxel + Doxorubicin + IL-12 gene + L-NMMA + Pembrolizumab Cyclophosphamide Docetaxel Doxorubicin IL-12 gene L-NMMA Pembrolizumab 0 1
Docetaxel + L-NMMA Docetaxel L-NMMA 0 1
L-NMMA + Pembrolizumab L-NMMA Pembrolizumab 0 1

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