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Drug Name KU-59403
Trade Name
Synonyms KU59403|KU 59403
Drug Descriptions

KU-59403 is an ATM inhibitor, which upon inhibition of Atm may lead to increased sensitivity to chemotherapuetic agents such as those inducing double strand breaks, and radiotherapy, subsequently resulting in cytotoxicity and antitumor activity (PMID: 23512991).

DrugClasses ATM Inhibitor 11
CAS Registry Number 845932-30-1
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Camptothecin + KU-59403 Camptothecin KU-59403 0 0
Doxorubicin + KU-59403 Doxorubicin KU-59403 0 0
Etoposide + KU-59403 Etoposide KU-59403 0 0
Irinotecan + KU-59403 Irinotecan KU-59403 0 0
KU-59403 KU-59403 0 0


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