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Drug Name Camptothecin
Trade Name
Synonyms 21,22-Secocamptothecin-21-oic acid lactone|Camptothecine
Drug Descriptions

Camptothecin is a natural product alkaloid topoisomerase I inhibitor from which irinotecan and topotecan are derived (PMID: 16990856, PMID: 32585151)

DrugClasses TOPO1 inhibitor 9
CAS Registry Number 7689-03-4
NCIT ID C338

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AG-14361 + Camptothecin AG-14361 Camptothecin 0 0
BAY1895344 + Camptothecin BAY1895344 Camptothecin 0 0
Berzosertib + Camptothecin Berzosertib Camptothecin 0 0
Camptothecin Camptothecin 0 0
Camptothecin + Ceralasertib Camptothecin Ceralasertib 0 0
Camptothecin + CHIR-124 CHIR-124 Camptothecin 2 0
Camptothecin + Enzalutamide Camptothecin Enzalutamide 0 0
Camptothecin + Gedatolisib Camptothecin Gedatolisib 0 0
Camptothecin + KU-55933 Camptothecin KU-55933 0 0
Camptothecin + KU-59403 Camptothecin KU-59403 0 0
Camptothecin + NU6027 Camptothecin NU6027 0 0
Camptothecin + Olaparib Camptothecin Olaparib 0 0
Camptothecin + OTS167 Camptothecin OTS167 0 0
Camptothecin + PV1019 Camptothecin PV1019 0 0
Camptothecin + VX-803 Camptothecin VX-803 0 0


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