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Drug Name VX-803
Trade Name
Synonyms M4344|VX80
Drug Descriptions

VX-803 (M4344) is an inhibitor of ATR that is used in combination with radiation or chemotherapy (PMID: 30645202, PMID: 31836456).

DrugClasses ATR Inhibitor 13
CAS Registry Number 1613191-99-3
NCIT ID C129693

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Camptothecin + VX-803 Camptothecin VX-803 0 0
Carboplatin + VX-803 Carboplatin VX-803 0 1
Cisplatin + VX-803 Cisplatin VX-803 0 0
Etoposide + VX-803 Etoposide VX-803 0 0
Exatecan mesylate + VX-803 Exatecan mesylate VX-803 0 0
Gemcitabine + VX-803 Gemcitabine VX-803 0 0
Indotecan + VX-803 Indotecan VX-803 0 0
Irinotecan + VX-803 Irinotecan VX-803 0 0
Niraparib + VX-803 Niraparib VX-803 0 2
SN-38 + VX-803 SN-38 VX-803 0 0
Talazoparib + VX-803 Talazoparib VX-803 0 0
Topotecan + VX-803 Topotecan VX-803 0 0
VX-803 VX-803 0 1


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