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Drug Name NU6027
Trade Name
Drug Descriptions

NU6027 is a small molecule inhibitor of ATR and CDK2, which may enhance the sensitivity of chemotherapeutic agents and result in decreased cell survival (PMID: 21730979, PMID: 27355194).

DrugClasses ATR Inhibitor 14 CDK2 Inhibitor 23
CAS Registry Number 220036-08-8


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Camptothecin + NU6027 Camptothecin NU6027 0 0
Cisplatin + NU6027 Cisplatin NU6027 0 0
Doxorubicin + NU6027 Doxorubicin NU6027 0 0
Hydroxyurea + NU6027 Hydroxyurea NU6027 0 0
NU6027 NU6027 0 0
NU6027 + Rucaparib NU6027 Rucaparib 0 0
NU6027 + Temozolomide NU6027 Temozolomide 1 0

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