Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Ceralasertib
Trade Name
Synonyms AZD6738|AZD-6738
Drug Descriptions

Ceralasertib (AZD6738) is an inhibitor of ATR, which may enhance the sensitivity of chemotherapeutic agents, potentially resulting in tumor regression (PMID: 26517239, PMID: 31836456).

DrugClasses ATR Inhibitor 16
CAS Registry Number 1352226-88-0
NCIT ID C111993

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Ceralasertib Acalabrutinib Ceralasertib 0 1
Camptothecin + Ceralasertib Camptothecin Ceralasertib 0 0
Carboplatin + Ceralasertib Carboplatin Ceralasertib 0 1
Carboplatin + Ceralasertib + Durvalumab + Etoposide Carboplatin Ceralasertib Durvalumab Etoposide 0 1
Ceralasertib Ceralasertib 5 8
Ceralasertib + Cisplatin Ceralasertib Cisplatin 1 0
Ceralasertib + Cisplatin + Durvalumab + Etoposide Ceralasertib Cisplatin Durvalumab Etoposide 0 1
Ceralasertib + Durvalumab Ceralasertib Durvalumab 2 5
Ceralasertib + Durvalumab + Nab-paclitaxel Ceralasertib Durvalumab Nab-paclitaxel 0 1
Ceralasertib + Gemcitabine Ceralasertib Gemcitabine 0 1
Ceralasertib + Ibrutinib Ceralasertib Ibrutinib 2 0
Ceralasertib + LB-100 Ceralasertib LB-100 0 0
Ceralasertib + Niraparib Ceralasertib Niraparib 1 0
Ceralasertib + Olaparib Ceralasertib Olaparib 9 12
Ceralasertib + Paclitaxel Ceralasertib Paclitaxel 0 0
Ceralasertib + Radiotherapy Ceralasertib Radiotherapy 4 0
Ceralasertib + STP-B Ceralasertib STP-B 0 0
Ceralasertib + Talazoparib Ceralasertib Talazoparib 1 0
Ceralasertib + Trastuzumab deruxtecan Ceralasertib Trastuzumab deruxtecan 0 1


Additional content available in CKB BOOST