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Drug Name Rintatolimod
Trade Name
Synonyms Ampligen|Atvogen|Poly(I).Poly(c12,U)
Drug Descriptions

Rintatolimod (Ampligen) is a synthetic dsRNA molecule that activates TLR3 and other interferon-induced proteins, which may result in increased anti-tumor immune response (PMID: 27045557, PMID: 19200817).

DrugClasses
CAS Registry Number 38640-92-5
NCIT ID C1001

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Therapy Name Drugs Efficacy Evidence Clinical Trials
alphaDC1 + Celecoxib + Interferon alpha-2b + Rintatolimod Celecoxib Interferon alpha-2b Rintatolimod alphaDC1 0 1
Anti-HER2/HER3 DC vaccine + Celecoxib + Interferon alpha-2b + Pembrolizumab + Rintatolimod Anti-HER2/HER3 DC vaccine Celecoxib Interferon alpha-2b Pembrolizumab Rintatolimod 0 1
Anti-HER2/HER3 DC vaccine + Celecoxib + Interferon alpha-2b + Rintatolimod Anti-HER2/HER3 DC vaccine Celecoxib Interferon alpha-2b Rintatolimod 0 1
Aspirin + Interferon alpha-2b + Rintatolimod Aspirin Interferon alpha-2b Rintatolimod 0 1
Aspirin + Rintatolimod Aspirin Rintatolimod 0 1
Celecoxib + Cisplatin + Interferon alpha-2b + Rintatolimod Celecoxib Cisplatin Interferon alpha-2b Rintatolimod 0 1
Celecoxib + Cyclophosphamide + Doxorubicin + Interferon alpha-2b + Paclitaxel + Rintatolimod Celecoxib Cyclophosphamide Doxorubicin Interferon alpha-2b Paclitaxel Rintatolimod 0 1
Celecoxib + Interferon alpha-2b + Pembrolizumab + Rintatolimod Celecoxib Interferon alpha-2b Pembrolizumab Rintatolimod 0 2
Celecoxib + Interferon alpha-2b + Rintatolimod Celecoxib Interferon alpha-2b Rintatolimod 0 1
Cisplatin + Pembrolizumab + Rintatolimod Cisplatin Pembrolizumab Rintatolimod 0 1
Durvalumab + Rintatolimod Durvalumab Rintatolimod 0 1
Pembrolizumab + Rintatolimod Pembrolizumab Rintatolimod 0 1
Rintatolimod Rintatolimod 0 1


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