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Drug Name AB928
Trade Name
Synonyms AB 928|AB-928
Drug Descriptions

AB928 is an antagonist of the adenosine receptors A2aR and A2bR, which may relieve adenosine-mediated immune suppression and lead to enhanced anti-tumor activity in combination with other agents (European Journal of Cancer, Vol 92, S14-S15).

DrugClasses Adenosine Targeting 18

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB154 + AB928 + GLS-010 AB154 AB928 GLS-010 0 1
AB680 + AB928 AB680 AB928 0 1
AB680 + AB928 + GLS-010 AB680 AB928 GLS-010 0 1
AB928 AB928 0 0
AB928 + Carboplatin + Pembrolizumab + Pemetrexed Disodium AB928 Carboplatin Pembrolizumab Pemetrexed Disodium 0 1
AB928 + Carboplatin + Pemetrexed Disodium AB928 Carboplatin Pemetrexed Disodium 0 1
AB928 + Docetaxel + GLS-010 AB928 Docetaxel GLS-010 0 1
AB928 + Doxorubicin AB928 Doxorubicin 1 0
AB928 + Enzalutamide + GLS-010 AB928 Enzalutamide GLS-010 0 1
AB928 + Fluorouracil + Leucovorin + Oxaliplatin AB928 Fluorouracil Leucovorin Oxaliplatin 0 1
AB928 + GLS-010 AB928 GLS-010 0 2
AB928 + IPI-549 + Pegylated liposomal-doxorubicin AB928 IPI-549 Pegylated liposomal-doxorubicin 0 1
AB928 + Oxaliplatin AB928 Oxaliplatin 1 0
AB928 + Pegylated liposomal-doxorubicin AB928 Pegylated liposomal-doxorubicin 0 1


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