Drug Detail


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Drug Name AB154
Trade Name
Synonyms AB-154|AB 154|Domvanalimab
Drug Descriptions

AB154 (domvanalimab) is a monoclonal antibody that targets T-cell immunoreceptor with Ig and ITIM domains (TIGIT), potentially resulting in enhanced immune response (Cancer Immunol Res 2019;7(2 Suppl):Abstract nr A124).

DrugClasses Immune Checkpoint Inhibitor 147 TIGIT Antibody 14
CAS Registry Number NA
NCIT ID C162875


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB154 AB154 0 2
AB154 + AB928 + Zimberelimab AB154 AB928 Zimberelimab 0 2
AB154 + APX005M + Zimberelimab AB154 APX005M Zimberelimab 0 1
AB154 + Durvalumab AB154 Durvalumab 0 1
AB154 + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab AB154 Fluorouracil Leucovorin Oxaliplatin Zimberelimab 0 1
AB154 + Zimberelimab AB154 Zimberelimab 0 5

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