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Drug Name PD-L1.t-haNK cells
Trade Name
Synonyms PD-L1 t-haNK|Allogeneic PD-L1-t-haNK
Drug Descriptions

PD-L1.t-haNK cells are natural killer (NK) cells engineered to express a chimeric antigen receptor (CAR) that targets PD-L1, which may induce cell killing in PD-L1-expressing tumor cells resulting in decreased tumor growth (PMID: 32439799).

CAS Registry Number NA
NCIT ID C174011


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldoxorubicin + ALT-803 + Cyclophosphamide + Gemcitabine + Nab-paclitaxel + PD-L1.t-haNK cells ALT-803 Aldoxorubicin Cyclophosphamide Gemcitabine Nab-paclitaxel PD-L1.t-haNK cells 0 1
ALT-803 + Cyclophosphamide + PD-L1.t-haNK cells + Sacituzumab govitecan-hziy ALT-803 Cyclophosphamide PD-L1.t-haNK cells Sacituzumab govitecan-hziy 0 1
ALT-803 + PD-L1.t-haNK cells + Pembrolizumab ALT-803 PD-L1.t-haNK cells Pembrolizumab 0 1
PD-L1.t-haNK cells PD-L1.t-haNK cells 0 1

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