Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name CAR.k.28 cells
Trade Name
Synonyms ATLCAR.k.28|ATLCAR.kappa.28
Drug Descriptions

CAR.k.28 cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor targeting the Kappa-light chain antibody linked to CD28 endodomain, which potentially induces cytotoxicity against Kappa-positive tumor cells (PMID: 16926291).



  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bendamustine + CAR.k.28 cells + Fludarabine Bendamustine CAR.k.28 cells Fludarabine 0 1
CAR.k.28 cells CAR.k.28 cells 2 1
CAR.k.28 cells + Cyclophosphamide + Fludarabine CAR.k.28 cells Cyclophosphamide Fludarabine 0 1

Additional content available in CKB BOOST