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Drug Name Anetumab ravtansine
Trade Name
Synonyms BAY94-9343|BAY 94-9343
Drug Descriptions

Anetumab ravtansine (BAY94-9343) is a monoclonal antibody against mesothelin (MSLN) in conjugation with maytansinoid DM4, which delivers maytansinoid DM4 to tumor cells over expressing mesothelin, resulting in tumor cell death (PMID: 24714131, PMID: 32815024, PMID: 32213105).

DrugClasses MSLN Antibody 10
CAS Registry Number 1375258-01-7
NCIT ID C98293

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anetumab ravtansine Anetumab ravtansine 0 5
Anetumab ravtansine + Atezolizumab Anetumab ravtansine Atezolizumab 0 1
Anetumab ravtansine + Bevacizumab Anetumab ravtansine Bevacizumab 0 1
Anetumab ravtansine + Cisplatin Anetumab ravtansine Cisplatin 0 1
Anetumab ravtansine + Cisplatin + Pemetrexed Disodium Anetumab ravtansine Cisplatin Pemetrexed Disodium 0 1
Anetumab ravtansine + Gemcitabine Anetumab ravtansine Gemcitabine 0 1
Anetumab ravtansine + Gemcitabine + Nivolumab Anetumab ravtansine Gemcitabine Nivolumab 0 1
Anetumab ravtansine + Ipilimumab + Nivolumab Anetumab ravtansine Ipilimumab Nivolumab 0 1
Anetumab ravtansine + Itraconazole Anetumab ravtansine Itraconazole 0 1
Anetumab ravtansine + Nivolumab Anetumab ravtansine Nivolumab 0 1
Anetumab ravtansine + Pembrolizumab Anetumab ravtansine Pembrolizumab 0 1


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