Drug Detail


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Drug Name RO7247669
Trade Name
Synonyms RO-7247669|RO 7247669|tobemstomig
Drug Descriptions

RO7247669 is a bispecific antibody that targets both PD-1 (PDCD1; CD279) and LAG3, potentially resulting in restoration of T-lymphocyte function and antitumor activity (Annals of Oncology 33 (2022): S884-S885).

DrugClasses LAG3 Antibody 18 PD-L1/PD-1 antibody 117
CAS Registry Number 2648839-43-2
NCIT ID C173539


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Axitinib + RO7247669 Axitinib RO7247669 0 1
Axitinib + RO7247669 + Tiragolumab Axitinib RO7247669 Tiragolumab 0 1
Bevacizumab + RO7247669 Bevacizumab RO7247669 0 1
Carboplatin + Paclitaxel + RO7247669 Carboplatin Paclitaxel RO7247669 0 1
Carboplatin + Pemetrexed Disodium + RO7247669 Carboplatin Pemetrexed Disodium RO7247669 0 1
Nab-paclitaxel + RO7247669 Nab-paclitaxel RO7247669 0 1
Pemetrexed Disodium + RO7247669 Pemetrexed Disodium RO7247669 0 1
RO7247669 RO7247669 0 6
RO7247669 + Tiragolumab RO7247669 Tiragolumab 0 2

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