Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Bemcentinib
Trade Name
Synonyms BGB 324|BGB-324|BGB324|R428|R-428
Drug Descriptions

Bemcentinib (BGB-324) is a small molecule inhibitor of Axl, which inhibits tumor growth and may overcome EMT-mediated acquired drug resistance (PMID: 20145120, PMID: 31134766).

DrugClasses AXL Inhibitor 28
CAS Registry Number 1037624-75-1
NCIT ID C121854


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bemcentinib Bemcentinib 9 2
Bemcentinib + Ceritinib Bemcentinib Ceritinib 2 0
Bemcentinib + Cetuximab Bemcentinib Cetuximab 3 0
Bemcentinib + Cisplatin + Gemcitabine + Nab-paclitaxel Bemcentinib Cisplatin Gemcitabine Nab-paclitaxel 0 1
Bemcentinib + Crizotinib Bemcentinib Crizotinib 3 0
Bemcentinib + Docetaxel Bemcentinib Docetaxel 0 1
Bemcentinib + Erlotinib Bemcentinib Erlotinib 1 1
Bemcentinib + Imatinib Bemcentinib Imatinib 0 0
Bemcentinib + Metformin Bemcentinib Metformin 1 0
Bemcentinib + Olaparib Bemcentinib Olaparib 2 0
Bemcentinib + Pembrolizumab Bemcentinib Pembrolizumab 0 3
Bemcentinib + Radiotherapy Bemcentinib Radiotherapy 0 0
Bemcentinib + Vemurafenib Bemcentinib Vemurafenib 1 0

Additional content available in CKB BOOST