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|Therapy Name||Bemcentinib + Ceritinib|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Bemcentinib||BGB 324|BGB-324|BGB324|R428|R-428||AXL Inhibitor 28||Bemcentinib (BGB-324) is a small molecule inhibitor of Axl, which inhibits tumor growth and may overcome EMT-mediated acquired drug resistance (PMID: 20145120, PMID: 31134766).|
|Ceritinib||Zykadia||LDK378||ALK Inhibitor 29 ROS1 Inhibitor 19||Zykadia (ceritinib) inhibits ALK, including ALK mutations and fusions, and has additional activity against ROS1 fusions, potentially resulting in decreased tumor cell growth (PMID: 25322323, PMID: 26372962). Zykadia (ceritinib) is FDA approved for ALK-positive (rearrangements and fusions) metastatic non-small cell lung cancer (FDA.gov).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|