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Drug Name Ensartinib
Trade Name
Synonyms X-396
Drug Descriptions

Ensartinib (X-396) is a small molecule inhibitor of ALK, which inhibits downstream signaling and potentially leads to decreased growth of ALK-expressing tumors (PMID: 21613408, PMID: 31628085).

DrugClasses ALK Inhibitor 23

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Ensartinib Carboplatin Ensartinib 0 1
Cisplatin + Ensartinib Cisplatin Ensartinib 0 1
Durvalumab + Ensartinib Durvalumab Ensartinib 0 1
Ensartinib Ensartinib 21 8
Ensartinib + Sirolimus Ensartinib Sirolimus 1 0


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