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Drug Name Apatorsen
Trade Name
Synonyms OGX-427|ISIS 306053|OGX427|OGX 427|ISIS-306053|ISIS 306053
Drug Descriptions

Apatorsen (OGX-427) is an antisense oligonucleotide that targets HSBP1 (HSP27), which reduces Hsbp1 expression, potentially resulting in increased tumor cell apoptosis and improved sensitivity to other anti-tumor therapies (PMID: 31420467).

DrugClasses Antisense Therapy 13
CAS Registry Number 1002331-21-6
NCIT ID C71740


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Apatorsen Apatorsen 0 3
Apatorsen + Carboplatin + Pemetrexed Disodium Apatorsen Carboplatin Pemetrexed Disodium 0 0
Apatorsen + Gemcitabine Apatorsen Gemcitabine 0 0

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