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Apatorsen (OGX-427) is an antisense oligonucleotide that targets HSBP1 (HSP27), which reduces Hsbp1 expression, potentially resulting in increased tumor cell apoptosis and improved sensitivity to other anti-tumor therapies (PMID: 31420467).
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Apatorsen + Gemcitabine||Apatorsen Gemcitabine||0||0|