Drug Detail


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Drug Name ABBV-181
Trade Name
Synonyms ABBV181|ABBV 181|Budigalimab
Drug Descriptions

ABBV-181 (budigalimab) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 32770720).

DrugClasses Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 89
CAS Registry Number 2098225-93-3
NCIT ID C137682


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-011 + ABBV-181 ABBV-011 ABBV-181 0 1
ABBV-151 + ABBV-181 ABBV-151 ABBV-181 0 1
ABBV-181 ABBV-181 0 2
ABBV-181 + ABBV-368 + ABBV-927 ABBV-181 ABBV-368 ABBV-927 0 1
ABBV-181 + ABBV-368 + IMO-2125 + Nab-paclitaxel ABBV-181 ABBV-368 IMO-2125 Nab-paclitaxel 0 1
ABBV-181 + ABBV-514 ABBV-181 ABBV-514 0 1
ABBV-181 + ABBV-927 + Carboplatin ABBV-181 ABBV-927 Carboplatin 0 1
ABBV-181 + ABBV-927 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin ABBV-181 ABBV-927 Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
ABBV-181 + ABT-165 ABBV-181 ABT-165 0 1
ABBV-181 + ABT-165 + Paclitaxel ABBV-181 ABT-165 Paclitaxel 0 1
ABBV-181 + Fluorouracil + Leucovorin + Oxaliplatin + TTX-030 ABBV-181 Fluorouracil Leucovorin Oxaliplatin TTX-030 0 0
ABBV-181 + Rovalpituzumab Tesirine ABBV-181 Rovalpituzumab Tesirine 0 0
ABBV-181 + SC-003 ABBV-181 SC-003 0 1
ABBV-181 + SC-004 ABBV-181 SC-004 0 1
ABBV-181 + SC-006 ABBV-181 SC-006 0 0

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