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Drug Name Rovalpituzumab Tesirine
Trade Name
Synonyms Rova-T|SC16LD6.5
Drug Descriptions

Rovalpituzumab Tesirine (Rova-T) is an antibody drug conjugate of pyrrolobenzodiazepine (PBD) cytotoxin D6.5 and human anti-delta-like 3 (DLL3) antibody, which targets and kills DLL-3 expressing tumor cells (PMID: 26311731).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + Etoposide + Rovalpituzumab Tesirine Cisplatin Etoposide Rovalpituzumab Tesirine 0 1
Dexamethasone + Rovalpituzumab Tesirine Dexamethasone Rovalpituzumab Tesirine 0 2
Ipilimumab + Nivolumab + Rovalpituzumab Tesirine Ipilimumab Nivolumab Rovalpituzumab Tesirine 0 1
Nivolumab + Rovalpituzumab Tesirine Nivolumab Rovalpituzumab Tesirine 0 1
Rovalpituzumab Tesirine Rovalpituzumab Tesirine 0 6


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