Drug Detail


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Drug Name Vibostolimab
Trade Name
Synonyms MK7684|MK 7684|MK-7684
Drug Descriptions

Vibostolimab (MK-7684) acts as an antagonist to T-cell immunoreceptor with Ig and ITIM domains (TIGIT) by preventing the interaction of TIGIT with its ligands, NECTIN2 (CD112) and PVR (CD155), potentially resulting in enhanced anti-tumor immune response (NCI Drug Dictionary).

DrugClasses Immune Checkpoint Inhibitor 146 TIGIT Antibody 19
CAS Registry Number 2231305-30-7
NCIT ID C140041


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Paclitaxel + Pembrolizumab + Vibostolimab Carboplatin Paclitaxel Pembrolizumab Vibostolimab 0 1
Carboplatin + Pembrolizumab + Pemetrexed Disodium + Vibostolimab Carboplatin Pembrolizumab Pemetrexed Disodium Vibostolimab 0 1
MK-1308 + Pembrolizumab + Vibostolimab MK-1308 Pembrolizumab Vibostolimab 0 1
Pembrolizumab + Vibostolimab Pembrolizumab Vibostolimab 0 3
Vibostolimab Vibostolimab 0 1

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