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Drug Name SAR408701
Trade Name
Synonyms SAR-408701|Tusamitamab ravtansine
Drug Descriptions

SAR408701 is an anti-CEACAM5 antibody in conjugation with DM4, which may lead to specific toxicity towards CEACAM5-expressing tumor cells (Eu J Cancer Dec 2016, 69(Suppl 1):S14-S15).

DrugClasses CEACAM5 Antibody 7
CAS Registry Number 2254086-60-5
NCIT ID C117229

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Pembrolizumab + Pemetrexed Disodium + SAR408701 Carboplatin Pembrolizumab Pemetrexed Disodium SAR408701 0 1
Carboplatin + Pembrolizumab + SAR408701 Carboplatin Pembrolizumab SAR408701 0 1
Cisplatin + Pembrolizumab + SAR408701 Cisplatin Pembrolizumab SAR408701 0 1
Cisplatin + Pemetrexed Disodium + SAR408701 Cisplatin Pemetrexed Disodium SAR408701 0 1
Diphenhydramine + SAR408701 Diphenhydramine SAR408701 0 0
Gemcitabine + SAR408701 Gemcitabine SAR408701 0 1
Pembrolizumab + Ramucirumab + SAR408701 Pembrolizumab Ramucirumab SAR408701 0 1
Pembrolizumab + SAR408701 Pembrolizumab SAR408701 0 1
Ramucirumab + SAR408701 Ramucirumab SAR408701 0 2
SAR408701 SAR408701 0 6


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