Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Dostarlimab
Trade Name
Synonyms TSR-042
Drug Descriptions

Dostarlimab (TSR-042) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (Eur J Cancer 2016 Dec; 69 (Suppl 1):S102, Abstract # 310, PMID: 31847708, PMID: 32213091).

DrugClasses Immune Checkpoint Inhibitor 98 PD-L1/PD-1 antibody 68
CAS Registry Number 2022215-59-2
NCIT ID C126799


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Dostarlimab + Niraparib Bevacizumab Dostarlimab Niraparib 0 1
Capecitabine + Dostarlimab Capecitabine Dostarlimab 0 1
Carboplatin + Dostarlimab + Paclitaxel Carboplatin Dostarlimab Paclitaxel 0 2
Docetaxel + Dostarlimab Docetaxel Dostarlimab 0 1
Docetaxel + Dostarlimab + TSR-022 Docetaxel Dostarlimab TSR-022 0 1
Dostarlimab Dostarlimab 1 4
Dostarlimab + Fluorouracil Dostarlimab Fluorouracil 0 1
Dostarlimab + GSK6097608 Dostarlimab GSK6097608 0 1
Dostarlimab + Niraparib Dostarlimab Niraparib 0 11
Dostarlimab + TSR-022 Dostarlimab TSR-022 0 2
Dostarlimab + TSR-033 Dostarlimab TSR-033 1 0

Additional content available in CKB BOOST