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Drug Name Dostarlimab
Trade Name
Synonyms TSR-042
Drug Descriptions

Dostarlimab (TSR-042) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (Eur J Cancer 2016 Dec; 69 (Suppl 1):S102, Abstract # 310, PMID: 31847708).

DrugClasses Immune Checkpoint Inhibitor 95 PD-L1/PD-1 antibody 62

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Dostarlimab + Niraparib Bevacizumab Dostarlimab Niraparib 0 1
Capecitabine + Dostarlimab Capecitabine Dostarlimab 0 1
Carboplatin + Dostarlimab + Paclitaxel Carboplatin Dostarlimab Paclitaxel 0 2
Dostarlimab Dostarlimab 1 3
Dostarlimab + Niraparib Dostarlimab Niraparib 0 5
Dostarlimab + TSR-022 Dostarlimab TSR-022 0 2
Dostarlimab + TSR-033 Dostarlimab TSR-033 1 0


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