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| Drug Name | BGBA1217 |
| Trade Name | |
| Synonyms | BGB-A1217|BGB A1217|Ociperlimab |
| Drug Descriptions |
BGBA1217 is a monoclonal antibody that binds to TIGIT and blocks its interaction with Nectin-2 (CD112) and Nectin-like protein 5 (CD155), which results in increased interaction of CD112 and CD155 with the co-stimulatory receptor CD226 and activation of downstream signaling, potentially inducing immune response against tumor cells (NCI Thesaurus, Ann Oncol (2023) 34 (suppl_2): S862). |
| DrugClasses | TIGIT Antibody 19 |
| CAS Registry Number | 2342597-93-5 |
| NCIT ID | C170906 |
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