Drug Detail


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Drug Name X4P-001
Trade Name
Synonyms Mavorixafor|X4P-001-IO|AMD-070|AMD-11070|AMD11070
Drug Descriptions

Mavorixafor (X4P-001), is a CXCR4 antagonist, which blocks the binding of CXCL12 to prevent metastasis and may activate cytotoxic T-lymphocytes (PMID: 23538388).

DrugClasses CXCR4 Inhibitor 15
CAS Registry Number 558447-26-0
NCIT ID C126660


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Axitinib + X4P-001 Axitinib X4P-001 0 0
Ibrutinib + X4P-001 Ibrutinib X4P-001 0 1
Nivolumab + X4P-001 Nivolumab X4P-001 0 1
Pembrolizumab + X4P-001 Pembrolizumab X4P-001 0 1
X4P-001 X4P-001 0 1

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