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Drug Name RO7283420
Trade Name
Synonyms RO-7283420|RO 7283420|RG6007|RG-6007|RG 6007|HLA-A2-WT1 x CD3 RG6007
Drug Descriptions

RO7283420 is a T-cell receptor-like T-cell engaging bispecific antibody (T-BsAb) that targets a 9-amino acid peptide derived from Wilms tumor 1 (WT1) and CD3 expressed on T-lymphocytes, which potentially leads to a cytotoxic T-lymphocyte response against tumor cells expressing WT1 (NCI Drug Dictionary).

DrugClasses CD3 Antibody 93
CAS Registry Number NA
NCIT ID C188287

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Dasatinib + RO7283420 + Tocilizumab Dasatinib RO7283420 Tocilizumab 0 1
RO7283420 RO7283420 0 0


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