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Drug Name Teclistamab
Trade Name Tecvayli
Synonyms JNJ-64007957|BCMAxCD3|JNJ 64007957|JNJ64007957
Drug Descriptions

Tecvayli (teclistamab) is a bispecific antibody that targets CD3 and BCMA, potentially resulting in increased immune response against BCMA-expressing tumor cells (Blood Dec 2016, 128 (22) 5668). Tecvayli (teclistamab) is FDA approved for use in adult patients with relapsed or refractory multiple myeloma who have received four or more prior lines of therapy (FDA.gov).

DrugClasses CD3 Antibody 63
CAS Registry Number 2119595-80-9
NCIT ID C136823

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bortezomib + Daratumumab + Lenalidomide + Teclistamab Bortezomib Daratumumab Lenalidomide Teclistamab 0 1
Daratumumab + Lenalidomide + Teclistamab Daratumumab Lenalidomide Teclistamab 0 1
Daratumumab + Pomalidomide + Teclistamab Daratumumab Pomalidomide Teclistamab 0 1
Daratumumab + Teclistamab Daratumumab Teclistamab 0 2
Lenalidomide + Teclistamab Lenalidomide Teclistamab 0 1
Nirogacestat + Teclistamab Nirogacestat Teclistamab 0 1
Talquetamab + Teclistamab Talquetamab Teclistamab 0 1
Talquetamab + Teclistamab + unspecified PD-1 antibody Talquetamab Teclistamab unspecified PD-1 antibody 0 1
Teclistamab Teclistamab 0 5


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