Drug Detail


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Drug Name Monalizumab
Trade Name
Synonyms NN-8765|IPH-2201|IPH 2201|IPH2201
Drug Descriptions

Monalizumab (IPH2201) is a humanized monoclonal antibody against NKG2A that blocks NKG2A ligand binding, which in turn induces cell-mediated immune response against cancer cells (PMID: 30503213, PMID: 31623687, PMID: 31308062).

DrugClasses NKG2A Antibody 3
CAS Registry Number 1228763-95-8
NCIT ID C120208


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Durvalumab + Etoposide + Monalizumab Carboplatin Durvalumab Etoposide Monalizumab 0 1
Cetuximab + Monalizumab Cetuximab Monalizumab 0 2
Cisplatin + Durvalumab + Etoposide + Monalizumab Cisplatin Durvalumab Etoposide Monalizumab 0 1
Durvalumab + Fluorouracil + Leucovorin + Monalizumab + Oxaliplatin Durvalumab Fluorouracil Leucovorin Monalizumab Oxaliplatin 0 1
Durvalumab + Monalizumab Durvalumab Monalizumab 0 7
Ibrutinib + Monalizumab Ibrutinib Monalizumab 0 1
MEDI5752 + Monalizumab MEDI5752 Monalizumab 0 1
Monalizumab Monalizumab 0 2

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