Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Atovaquone
Trade Name Mepron
Drug Descriptions

Mepron (atovaquone) is an anti-malarial drug typically used to treat pneumocystis pneumonia and toxoplasmosis, however, may also have an effect on cancer stem cells via the Warburg effect, potentially resulting in decreased cell proliferation and apoptosis (PMID: 27136895).

CAS Registry Number 95233-18-4
NCIT ID C28838


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Atovaquone Atovaquone 0 2
Atovaquone + Cytarabine + Daunorubicin + Etoposide Atovaquone Cytarabine Daunorubicin Etoposide 0 1
Atovaquone + Cytarabine + Daunorubicin + Gemtuzumab ozogamicin Atovaquone Cytarabine Daunorubicin Gemtuzumab ozogamicin 0 1

Additional content available in CKB BOOST