Drug Detail


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Drug Name ZEN-3694
Trade Name
Synonyms ZEN003694|BETi ZEN-3694|ZEN3694|ZEN 3694
Drug Descriptions

ZEN-3694 is a pan BET inhibitor that suppresses AR signaling, which potentially inhibits tumor progression (Cancer Res 2016;76(14 Suppl):Abstract nr LB-207, PMID: 32694156).

DrugClasses BET Inhibitor (Pan) 32
CAS Registry Number NA
NCIT ID C126805


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Binimetinib + ZEN-3694 Binimetinib ZEN-3694 0 1
Cisplatin + Etoposide + ZEN-3694 Cisplatin Etoposide ZEN-3694 0 1
Cisplatin + ZEN-3694 Cisplatin ZEN-3694 0 0
Entinostat + ZEN-3694 Entinostat ZEN-3694 0 1
Enzalutamide + Pembrolizumab + ZEN-3694 Enzalutamide Pembrolizumab ZEN-3694 0 1
Enzalutamide + ZEN-3694 Enzalutamide ZEN-3694 0 3
Ipilimumab + Nivolumab + ZEN-3694 Ipilimumab Nivolumab ZEN-3694 0 1
Nab-paclitaxel + Pembrolizumab + ZEN-3694 Nab-paclitaxel Pembrolizumab ZEN-3694 0 1
Nivolumab + ZEN-3694 Nivolumab ZEN-3694 0 1
Talazoparib + ZEN-3694 Talazoparib ZEN-3694 0 3
ZEN-3694 ZEN-3694 0 2

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