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Drug Name | Debio 0123 |
Trade Name | |
Synonyms | Debio-0123|Debio0123 |
Drug Descriptions |
Debio 0123 is an ATP-competitive inhibitor of Wee1 that suppresses CDK1 phosphorylation, which may lead to tumor growth inhibition (Cancer Res 2019;79(13 Suppl):Abstract nr 4423). |
DrugClasses | WEE1 Inhibitor 7 |
CAS Registry Number | NA |
NCIT ID | C173426 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + Debio 0123 | Carboplatin Debio 0123 | 0 | 1 |
Carboplatin + Debio 0123 + Etoposide | Carboplatin Debio 0123 Etoposide | 0 | 1 |
Debio 0123 | Debio 0123 | 0 | 1 |
Debio 0123 + Temozolomide | Debio 0123 Temozolomide | 0 | 1 |