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Drug Name | RRx-001 |
Trade Name | |
Synonyms | |
Drug Descriptions |
RRx-001 is a nitric oxide donor that is activated by hypoxia, leading to increased oxygen level in tumor and sensitizes tumor to radiotherapy (PMID: 26164533, PMID: 32169409). |
DrugClasses | |
CAS Registry Number | 925206-65-1 |
NCIT ID | C97130 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cisplatin + RRx-001 | Cisplatin RRx-001 | 0 | 1 |
Irinotecan + RRx-001 | Irinotecan RRx-001 | 0 | 1 |
Irinotecan + RRx-001 + Temozolomide | Irinotecan RRx-001 Temozolomide | 0 | 1 |
RRx-001 | RRx-001 | 0 | 4 |
RRx-001 + Temozolomide | RRx-001 Temozolomide | 0 | 1 |