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Drug Name HPVST cells
Trade Name
Synonyms Autologous HPV-16/18 E6/E7-specific TGF-beta-resistant T Lymphocytes
Drug Descriptions

HPVST cells are autologous T cells that are stimulated with HPV-16/18-loaded dendritic cells and are also engineered to express a dominant-negative TGF-beta receptor II that inhibits TGF-beta signaling, which potentially results in increased T cell response against HPV-16/18-positive tumor cells (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C121537

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + Fludarabine + HPVST cells + Nivolumab Cyclophosphamide Fludarabine HPVST cells Nivolumab 0 1
HPVST cells HPVST cells 0 1


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