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Drug Name anti-KRAS G12D mTCR cells
Trade Name
Synonyms
Drug Descriptions

Anti-KRAS G12D murine T-cell receptor (mTCR) cells are peripheral blood lymphocytes that have been transduced with a murine T-cell receptor that recognizes KRAS G12D, which may result in decreased growth of tumors harboring KRAS G12D (PMID: 26701267).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldesleukin + anti-KRAS G12D mTCR cells + Cyclophosphamide + Fludarabine Aldesleukin Cyclophosphamide Fludarabine anti-KRAS G12D mTCR cells 0 1
anti-KRAS G12D mTCR cells anti-KRAS G12D mTCR cells 0 0


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