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|Drug Name||CISH-inactivated autologous TILs|
|Synonyms||Autologous CISH-inactivated TILs|CISH inactivated TIL|
CISH-inactivated autologous TILs are patient-derived tumor infiltrating lymphocytes engineered to have disruption of cytokine-induced SH2 protein (CISH), which potentially results increased anti-tumor immune response (PMID: 36007524).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Aldesleukin + CISH-inactivated autologous TILs + Cyclophosphamide + Fludarabine||Aldesleukin CISH-inactivated autologous TILs Cyclophosphamide Fludarabine||0||2|
|CISH-inactivated autologous TILs||CISH-inactivated autologous TILs||0||0|
|CISH-inactivated autologous TILs + unspecified PD-1 antibody||CISH-inactivated autologous TILs unspecified PD-1 antibody||0||0|