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Drug Name | REGN5458 |
Trade Name | |
Synonyms | REGN-5458|REGN 5458|Anti-BCMA/CD3 BiTE |
Drug Descriptions |
REGN5458 is a bispecific antibody that binds to TNFRSF17 (BCMA) and CD3 with potential antitumor activity (Blood (2019) 134 (Supplement_1): 3176). |
DrugClasses | CD3 Antibody 78 TNFRSF17 Antibody 14 |
CAS Registry Number | NA |
NCIT ID | C158504 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bortezomib + Dexamethasone + REGN5458 | Bortezomib Dexamethasone REGN5458 | 0 | 1 |
Carfilzomib + Dexamethasone + REGN5458 | Carfilzomib Dexamethasone REGN5458 | 0 | 1 |
Daratumumab + Dexamethasone + REGN5458 | Daratumumab Dexamethasone REGN5458 | 0 | 1 |
Dexamethasone + Lenalidomide + REGN5458 | Dexamethasone Lenalidomide REGN5458 | 0 | 1 |
REGN5458 | REGN5458 | 0 | 1 |