Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name AMG 701
Trade Name
Synonyms AMG-701|AMG701|BiTE Antibody AMG 701|Anti-BCMA/CD3 BiTE Antibody AMG 701
Drug Descriptions

AMG 701 is a bi-specific T-cell engager (BiTE) antibody that simultaneously binds to BCMA (TNFRSF17) and CD3, and activates cytotoxic T-lymphocytes against tumor cells expressing BCMA, potentially inducing death of BCMA expressing tumor cells (NCI Drug Dictionary).

DrugClasses CD3 Antibody 96 TNFRSF17 Antibody 19
CAS Registry Number NA
NCIT ID C147028

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
AMG 701 AMG 701 0 1
AMG 701 + Lenalidomide AMG 701 Lenalidomide 0 0


Additional content available in CKB BOOST