Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name ABBV-383
Trade Name
Synonyms TNB-383B|TNB383B|TNB 383B|ABBV383|ABBV 383
Drug Descriptions

ABBV-383 (TNB-383B) is a bispecific antibody that targets alpha CD3 and BCMA, potentially resulting in the activation of T-cells and tumor cell lysis (Journal of Clinical Oncology 2018 36:15_suppl, 8034-8034, PMID: 36029527).

DrugClasses CD3 Antibody 63
CAS Registry Number NA
NCIT ID C164668

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-383 ABBV-383 0 2
ABBV-383 + Daratumumab + Dexamethasone ABBV-383 Daratumumab Dexamethasone 0 1
ABBV-383 + Dexamethasone + Lenalidomide ABBV-383 Dexamethasone Lenalidomide 0 1
ABBV-383 + Dexamethasone + Pomalidomide ABBV-383 Dexamethasone Pomalidomide 0 1
ABBV-383 + Nirogacestat ABBV-383 Nirogacestat 0 1


Additional content available in CKB BOOST