Drug Detail


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Drug Name ABBV-383
Trade Name
Synonyms TNB-383B|TNB383B|TNB 383B|ABBV383|ABBV 383
Drug Descriptions

ABBV-383 (TNB-383B) is a bispecific antibody that targets alpha CD3 and BCMA, potentially resulting in the activation of T-cells and tumor cell lysis (Journal of Clinical Oncology 2018 36:15_suppl, 8034-8034, PMID: 36029527).

DrugClasses CD3 Antibody 86 TNFRSF17 Antibody 17
CAS Registry Number NA
NCIT ID C164668


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-383 ABBV-383 0 3
ABBV-383 + Daratumumab + Dexamethasone ABBV-383 Daratumumab Dexamethasone 0 1
ABBV-383 + Dexamethasone + Lenalidomide ABBV-383 Dexamethasone Lenalidomide 0 1
ABBV-383 + Dexamethasone + Pomalidomide ABBV-383 Dexamethasone Pomalidomide 0 1
ABBV-383 + Nirogacestat ABBV-383 Nirogacestat 0 1

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