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Therapy Name Talquetamab
Synonyms
Therapy Description

Talquetamab (JNJ-64407564) is a bispecific antibody that targets CD3 and GPRC5D, potentially resulting in increased immune response against GPRC5D-expressing tumor cells (PMID: 32040549).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Talquetamab JNJ64407564|JNJ 64407564|JNJ-64407564 CD3 Antibody 78 Talquetamab (JNJ-64407564) is a bispecific antibody that targets CD3 and GPRC5D, potentially resulting in increased immune response against GPRC5D-expressing tumor cells (PMID: 32040549).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05461209 Phase III belantamab mafodotin-blmf Talquetamab A Study of Comparing Talquetamab to Belantamab Mafodotin in Participants With Relapsed/Refractory Multiple Myeloma (MonumenTAL-5) Withdrawn USA 1
NCT04634552 Phase II Talquetamab A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma Recruiting USA | FRA | ESP | DEU | BEL 6
NCT05503550 Expanded access Talquetamab Pre-Approval Access Single Patient Request for Talquetamab in Relapsed or Refractory Multiple Myeloma No longer available 0
NCT03399799 Phase I Talquetamab Dose Escalation Study of JNJ-64407564 in Participants With Relapsed or Refractory Multiple Myeloma Recruiting USA | ESP | BEL 1


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