Drug Detail


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Drug Name AZD7762
Trade Name
Synonyms AZD-7762
Drug Descriptions

AZD7762 is an ATP-competitive CHK1/CHK2 inhibitor, which abrogates DNA damage-induced cell cycle checkpoints, and demonstrates antitumor activity when administered in combination with DNA-damaging agents (PMID: 18790776, PMID: 32335582, PMID: 31372095).

DrugClasses CHK Inhibitor (Pan) 2
CAS Registry Number 860352-01-8
NCIT ID C66961


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD7762 AZD7762 2 0
AZD7762 + Berzosertib AZD7762 Berzosertib 0 0
AZD7762 + Cisplatin AZD7762 Cisplatin 1 0
AZD7762 + Gemcitabine AZD7762 Gemcitabine 0 0
AZD7762 + Hydroxyurea + VE-821 AZD7762 Hydroxyurea VE-821 0 0
AZD7762 + Irinotecan AZD7762 Irinotecan 0 0
AZD7762 + Ixazomib AZD7762 Ixazomib 0 0
AZD7762 + VE-821 AZD7762 VE-821 0 0

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