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Drug Name BMS-188667
Trade Name
Synonyms Abatacept|BMS 188667|BMS188667|RG2077|RG1046|CTLA4-IGG4M|Orencia
Drug Descriptions

Abatacept (BMS-188667) is a recombinant protein containing the extracellular domain of CTLA-4 fused to immunoglobulin G1, which binds to antigen presenting cells expressing CD80 and CD86 and blocks CD28-mediated activation of T cells, potentially enhancing immune suppression (PMID: 31189043, PMID: 32052309).

DrugClasses
CAS Registry Number 332348-12-6
NCIT ID C28898

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BMS-188667 BMS-188667 0 0
BMS-188667 + Dexamethasone + Ixazomib BMS-188667 Dexamethasone Ixazomib 0 1


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