Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name AZD2936
Trade Name
Synonyms AZD-2936|AZD 2936|Rilvegostomig
Drug Descriptions

AZD2936 is a bispecific antibody that targets T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) and PD-1 (PDCD1), which potentially leads to increased T-lymphocyte antitumor activity, tumor cell killing, and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2022;10).

DrugClasses PD-L1/PD-1 antibody 117 TIGIT Antibody 19
CAS Registry Number NA
NCIT ID C188211

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD2936 AZD2936 0 4
AZD2936 + Capecitabine AZD2936 Capecitabine 0 1
AZD2936 + Capecitabine + Oxaliplatin AZD2936 Capecitabine Oxaliplatin 0 1
AZD2936 + Carboplatin + Datopotamab deruxtecan AZD2936 Carboplatin Datopotamab deruxtecan 0 1
AZD2936 + Cisplatin + Gemcitabine AZD2936 Cisplatin Gemcitabine 0 1
AZD2936 + Datopotamab deruxtecan AZD2936 Datopotamab deruxtecan 0 2
AZD2936 + Fluorouracil + Leucovorin + Oxaliplatin AZD2936 Fluorouracil Leucovorin Oxaliplatin 0 1
AZD2936 + Gemcitabine + Tegafur-gimeracil-oteracil Potassium AZD2936 Gemcitabine Tegafur-gimeracil-oteracil Potassium 0 0
AZD2936 + Tegafur-gimeracil-oteracil Potassium AZD2936 Tegafur-gimeracil-oteracil Potassium 0 1


Additional content available in CKB BOOST