Drug Detail


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Drug Name AZD2936
Trade Name
Synonyms AZD-2936|AZD 2936|Rilvegostomig
Drug Descriptions

AZD2936 is a bispecific antibody that targets T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) and PD-1 (PDCD1), which potentially leads to increased T-lymphocyte antitumor activity, tumor cell killing, and inhibition of tumor growth (Journal for ImmunoTherapy of Cancer 2022;10).

DrugClasses PD-L1/PD-1 antibody 117 TIGIT Antibody 19
CAS Registry Number NA
NCIT ID C188211


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD2936 AZD2936 0 4
AZD2936 + Capecitabine AZD2936 Capecitabine 0 1
AZD2936 + Capecitabine + Oxaliplatin AZD2936 Capecitabine Oxaliplatin 0 1
AZD2936 + Carboplatin + Datopotamab deruxtecan AZD2936 Carboplatin Datopotamab deruxtecan 0 1
AZD2936 + Cisplatin + Gemcitabine AZD2936 Cisplatin Gemcitabine 0 1
AZD2936 + Datopotamab deruxtecan AZD2936 Datopotamab deruxtecan 0 2
AZD2936 + Fluorouracil + Leucovorin + Oxaliplatin AZD2936 Fluorouracil Leucovorin Oxaliplatin 0 1
AZD2936 + Gemcitabine + Tegafur-gimeracil-oteracil Potassium AZD2936 Gemcitabine Tegafur-gimeracil-oteracil Potassium 0 0
AZD2936 + Tegafur-gimeracil-oteracil Potassium AZD2936 Tegafur-gimeracil-oteracil Potassium 0 1

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