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Drug Name CV301
Trade Name
Synonyms CV-301|PANVAC|CV301-V/F|BN-CV301
Drug Descriptions

CV301 is a poxvirus-based vaccine that encodes tumor antigens CEA and MUC-1, and 3 costimulatory molecules including B7.1, ICAM-1, and LFA-3, which may stimulate antitumor immune response (PMID: 31110074).

DrugClasses
CAS Registry Number NA
NCIT ID C131129

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ALT-803 + CV301 + M7824 ALT-803 CV301 M7824 0 1
ALT-803 + CV301 + M7824 + NHS-IL12 ALT-803 CV301 M7824 NHS-IL12 0 1
Atezolizumab + CV301 Atezolizumab CV301 0 1
Bevacizumab + Capecitabine + CV301 + Durvalumab Bevacizumab CV301 Capecitabine Durvalumab 0 1
Capecitabine + CV301 + Durvalumab CV301 Capecitabine Durvalumab 0 1
CV301 CV301 1 0
CV301 + Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin CV301 Fluorouracil Leucovorin Nivolumab Oxaliplatin 0 1
CV301 + M7824 + PROSTVAC-F-TRICOM + PROSTVAC-V-TRICOM CV301 M7824 PROSTVAC-F-TRICOM PROSTVAC-V-TRICOM 0 1
CV301 + M7824 + SX-682 CV301 M7824 SX-682 0 0
CV301 + Nivolumab CV301 Nivolumab 0 1


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