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Drug Name Bemarituzumab
Trade Name
Synonyms FPA144
Drug Descriptions

Bemarituzumab (FPA144) is a monoclonal antibody against FGFR2 isoform B, which prevents ligand interaction and induces cell mediated cytotoxicity, potentially inhibiting proliferation and promoting apoptosis in cancer cells expressing FGFR2 isoform B (J Clin Oncol 32, 2014 (suppl; abstr e15074, PMID: 31094225, PMID: 32167861).

DrugClasses FGFR2 Antibody 3
CAS Registry Number 1952272-74-0
NCIT ID C120040

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bemarituzumab Bemarituzumab 0 3
Bemarituzumab + Docetaxel Bemarituzumab Docetaxel 0 1
Bemarituzumab + Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin Bemarituzumab Fluorouracil Leucovorin Nivolumab Oxaliplatin 0 1
Bemarituzumab + Fluorouracil + Leucovorin + Oxaliplatin Bemarituzumab Fluorouracil Leucovorin Oxaliplatin 0 2


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