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Drug Name NKR-2 cells
Trade Name
Synonyms NKG2D CAR-T cells|CYAD-01|CYAD-101
Drug Descriptions

NKR-2 cells are T-lymphocytes engineered to express a chimeric antigen receptor consists of human natural killer receptor (NKG2D) and the human CD3 zeta signaling domain, which may results in anti-tumor immunity (J Clin Oncol 35, 2017 (suppl; abstr TPS3093), PMID: 29133316).

DrugClasses
CAS Registry Number NA
NCIT ID C121536

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Fluorouracil + Irinotecan + Leucovorin + NKR-2 cells Fluorouracil Irinotecan Leucovorin NKR-2 cells 0 1
Fluorouracil + Leucovorin + NKR-2 cells + Oxaliplatin Fluorouracil Leucovorin NKR-2 cells Oxaliplatin 0 1
Fluorouracil + Leucovorin + NKR-2 cells + Oxaliplatin + Pembrolizumab Fluorouracil Leucovorin NKR-2 cells Oxaliplatin Pembrolizumab 0 1
NKR-2 cells NKR-2 cells 0 1


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